1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮
5-iodouridine
CAS: 1024-99-3
Molecular Formula: C9H11IN2O6
1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮 - Names and Identifiers
| Name | 5-iodouridine |
| Synonyms | NSC 523375 5-Iodoruidine 5-iodouridine 5-IODOURIDINE 5-Iodo-Uridine 5-Iodo-D-uridine Uridine, 5-iodo- (8CI)(9CI) 5-IODO-1-(BETA-D-RIBOFURANOSYL)URACIL 5-iodo-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione 2,4-dihydroxy-5-iodo-1-β-d-ribofuranosylpyrimidine 2,4-DIHYDROXY-5-IODO-1-BETA-D-RIBOFURANOSYLPYRIMIDINE 1-(β-D-Ribofuranosyl)-2-hydroxy-5-iodopyrimidine-4(1H)-one 1-β-D-Ribofuranosyl-2-hydroxy-5-iodo-1,4-dihydropyrimidine-4-one |
| CAS | 1024-99-3 |
| EINECS | 213-833-1 |
| InChI | InChI=1/C9H11IN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1 |
1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮 - Physico-chemical Properties
| Molecular Formula | C9H11IN2O6 |
| Molar Mass | 370.1 |
| Density | 2.27±0.1 g/cm3(Predicted) |
| Melting Point | 205-207 °C (dec.) (lit.) |
| Water Solubility | Soluble in water. |
| Appearance | Crystallization |
| Color | White |
| BRN | 33665 |
| pKa | 7.94±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Sensitive to light |
| Refractive Index | 1.748 |
| MDL | MFCD00006532 |
1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8-10 |
| HS Code | 29349990 |
1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮 - Introduction
5-Iodo-uridine, also known as 5-iodoguanosine, is an organic compound with the chemical formula C9H11IN2O6. The following is a description of the properties, uses, preparation and safety information of 5-iodo-uridine:
Nature:
1. Appearance: white crystalline powder.
2. melting point: about 200 degrees Celsius.
3. solubility: soluble in water and ethanol, slightly soluble in chloroform and ether.
Use:
1. It has antiviral effect on virus infection: 5-iodine-uridine can inhibit the replication of virus in cells and has antiviral effect.
2. Tumor treatment: The compound can be used as a sensitizer for radiation therapy for the treatment of certain types of tumors.
3. Research purposes: 5-iodo-uridine can be used as a tool to study the structure and function of RNA in the laboratory.
Preparation Method:
The preparation method of 5-iodo-uridine includes the following steps:
1. uridine after acidic treatment, removal of hydration groups in the nucleoside.
2. uridine reacts with cuprous iodide to generate uridine iodide.
3. iodinated uridine is dehydrated to generate 5-iodo-uridine.
Safety Information:
1. 5-iodo-uridine is an organic compound with certain toxicity and should follow the safety regulations for the operation of relevant chemicals.
2. in the operation should wear appropriate personal protective equipment, such as gloves, protective glasses, etc., to avoid direct contact with the skin and eyes.
3. storage should be sealed, away from the fire and flammable substances.
4. Avoid inhaling its dust, such as accidental inhalation or intake should be timely medical treatment and inform the doctor of the use of compounds.
Nature:
1. Appearance: white crystalline powder.
2. melting point: about 200 degrees Celsius.
3. solubility: soluble in water and ethanol, slightly soluble in chloroform and ether.
Use:
1. It has antiviral effect on virus infection: 5-iodine-uridine can inhibit the replication of virus in cells and has antiviral effect.
2. Tumor treatment: The compound can be used as a sensitizer for radiation therapy for the treatment of certain types of tumors.
3. Research purposes: 5-iodo-uridine can be used as a tool to study the structure and function of RNA in the laboratory.
Preparation Method:
The preparation method of 5-iodo-uridine includes the following steps:
1. uridine after acidic treatment, removal of hydration groups in the nucleoside.
2. uridine reacts with cuprous iodide to generate uridine iodide.
3. iodinated uridine is dehydrated to generate 5-iodo-uridine.
Safety Information:
1. 5-iodo-uridine is an organic compound with certain toxicity and should follow the safety regulations for the operation of relevant chemicals.
2. in the operation should wear appropriate personal protective equipment, such as gloves, protective glasses, etc., to avoid direct contact with the skin and eyes.
3. storage should be sealed, away from the fire and flammable substances.
4. Avoid inhaling its dust, such as accidental inhalation or intake should be timely medical treatment and inform the doctor of the use of compounds.
Last Update：2024-04-10 22:29:15
![1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮](http://res.chembk.com/assets/images/structure/300268.gif)
Supplier List
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 5-Iodouridine Visit Supplier Webpage Request for quotationCAS: 1024-99-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
1-[3,4-二羟基-5-(羟甲基)四氢呋喃-2-基]-5-碘嘧啶-2,4(1H,3H)-二酮
4-CYCLOPROPANECARBONYL-1H-PYRROLE-2-CARBOXYLIC ACID (3-METHOXY-PROPYL)-AMIDE
2-CHLORO-3-PYRIDYLAMINE3-氨基-2-氯吡啶
4-CYCLOPROPANECARBONYL-1H-PYRROLE-2-CARBOXYLIC ACID (3-METHOXY-PROPYL)-AMIDE
2-CHLORO-3-PYRIDYLAMINE3-氨基-2-氯吡啶